Study Investigating Tooth Movements With Conventional and Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) Supported Fixed Appliances

Not Applicable

• Conditions: Orthodontics; Tooth Movement
• Interventions: Procedure: orthodontic tx w/ conventional archwires+manual adjustments; Procedure: orthodontic treatment with customized archwires; Procedure: orthodontic treatment with prefabricated archwires

• Registration Number: NCT00871091
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

In orthodontics, conventional fixed appliances, usually consisting of prefabricated components, require step-by-step adjustment in order to move teeth in the planned direction.

May treatment be improved with customized archwires?

Study hypotheses:

* By using CAD/CAM in planning and fabrication of customized archwires, unnecessary tooth movements can be avoided and teeth can be moved on their direct path to the intended position.

* The application of CAD/CAM improves reproducibility, efficiency, and quality of orthodontic treatment.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-01
• Status Verified: 2009-03
• Study First Submitted: 2009-03-27
• Study First Submitted QC: 2009-03-27
• Last Update Submitted: 2009-03-27
• Study First Posted: 2009-03-30
• Last Update Posted: 2009-03-30
• Primary Completion: 2009-05
• Study Completion: 2009-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• treatment of front teeth with fixed orthodontic appliances is indicated
• complete secondary dentition
• age: 18-35
• in healthy general condition
• patient is informed about study and agrees to participate

Exclusion Criteria

• treatment of premolars and molars is necessary
• syndromes affecting bones and teeth
• cleft lip and palate
• inflammation or reduction (more than 50%) of periodontium
• intake of drugs affecting tooth movement and bone formation
• disturbance of bone formation
• disturbance of thyroidal function
• pregnancy
• participation in additional study affecting oral hygiene
• former therapy with ionized radiation or cytostatic drugs
• caries (active phase)
• alcohol dependency

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
3	orthodontic tx w/ conventional archwires+manual adjustments	prefabricated archwires with manual adjustments
1	orthodontic treatment with customized archwires	CAD/CAM group, customized archwires
2	orthodontic treatment with prefabricated archwires	prefabricated archwires (superelastic)

Primary Outcome Measures

Name	Time	Method
Sum of differences between resulted and shortest path of tooth movements in each patient	measurements every 14 days until end of treatment

Secondary Outcome Measures

Name	Time	Method
Difference between resulted and shortest path of movements for each tooth	measurements every 14 days until end of treatment

Trial Locations

Locations (1)

Department of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charité - Universitätsmedizin Berlin; 🇩🇪 Berlin, Germany