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Immediate antipyretic effect of Hufu Copper Guasha on sepsis patients with exogenous fever: a randomized controlled trial

Phase 1
Conditions
sepsis
Registration Number
ITMCTR2000003287
Lead Sponsor
Guangdong Provincial Hospital of Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. aged between 18 and 70 years;
2. patients consistent with the diagnosis of sepsis and exogenous fever;
3. axillary temperature between 38.0 and 40.0 degrees C;
4. hyperthermia within 2 days;
5. sequential organ failure assessment (SOFA) <= 3 points;
6. patients sign the informed consent form voluntarily.

Exclusion Criteria

1. pregnant and lactating women;
2. patients with central nervous fever;
3. patients with diabetes, malignancy or mental illness;
4. patients with coagulopathy;
5. patients with scar constitution and positive skin scratch test;
6. patients with A and B acute infectious diseases;
7. patients who have used other antipyretic drugs;
8. those with skin rashes, breakages, blisters, or ulcers on the surface of the Guasha area;
9. fever with convulsions, seizures, and closure.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
body temperature (axillary temperature);
Secondary Outcome Measures
NameTimeMethod
Interleukin 6 (IL-6);procalcitonin (PCT);tumor necrosis factor–a (TNF-a);C-reactive protein (CPR);white blood cell (WBC);
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