Influence of Inguinal Hernia Repair on Sperm Autoimmunity

Completed

• Conditions: Male Infertility Due to Antisperm Antibody
• Interventions: Diagnostic Test: Mar test

• Registration Number: NCT04591470
• Lead Sponsor: Istituto Clinico Humanitas

Brief Summary

Influence of inguinal hernia repair on sperm autoimmunity using MAR test

Detailed Description

All infertile male patients, visited between February 2000 and September 2020 and which were tested with MAR (Mixed Autoglobulin Reaction) test, were included in this retrospective study. Sperm quality (number of spermatozoa, motility, vitality and normal forms) were also studied in this patients. The aim of the study is to evaluate if there is a higher incidence of positive MAR test among patients undergoing inguinal hernioplasty compared to the general population

Study Timeline

• Study Start: 2020-06-01
• Status Verified: 2020-10
• Primary Completion: 2020-10-01
• Study Completion: 2020-10-01
• Study First Submitted: 2020-10-10
• Study First Submitted QC: 2020-10-10
• Study First Posted: 2020-10-19
• Last Update Submitted: 2020-11-04
• Last Update Posted: 2020-11-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 2415

Inclusion Criteria

• Patients undergone to correction of inguinal hernia

Exclusion Criteria

• No specific exclusion criteria were set.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
General population	Mar test	-
Pazients undergone inguinal hernia correction	Mar test	-

Primary Outcome Measures

Name	Time	Method
Evaluate if there is a higher incidence of positive MAR test among patients undergoing inguinal hernioplasty	20 years

Secondary Outcome Measures

Name	Time	Method
Evaluate if there is a modification of seminal parameters among patients undergoing inguinal hernioplasty	20 years

Trial Locations

Locations (1)

Istituto Clinico Humanitas; 🇮🇹 Rozzano, Milano, Italy