跳至主要内容
临床试验/NCT06718283
NCT06718283招募中不适用

Assessment of Hematologic Indices in Juvenile Lupus Erythematosus Patients : Correlation With Disease Activity and Chronic Organ Damage in These Patients

Sohag University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2024年11月30日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
50
试验地点
1
主要终点
Calculation of hematological indices in juvenile lupus erythematosus patients

研究概览

简要总结

The study aim to evaluate the relationship between some important hematologic indices in juvenile lupus erythematosus patients and if these indices may be use as markers of disease acitivity in these patients or not ,also evaluate the relationship with these markers and chronic organ damage index

详细描述

We calculate important hematologic indices in children diagnosed as SLE as systemic inflamatory index ,systemic inflamatory response index and aggregate index of systemic inflamation in these patients ,and correlate these indices with SLE disease activity index and chronic damage index in these patients.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
— 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • patients who fillful 2012 SLICC criteria or 2019 ACR/EULAR criteria of systemic lupus erythematosus
  • Age of patients at disease onset before 18 years

排除标准

  • Adult onset disease ( age at disease onset after 18 years
  • Any other chronic inflamatory disorders or other autoimmune diseases

结局指标

主要结局

Calculation of hematological indices in juvenile lupus erythematosus patients

时间窗: 3_ 6 months

Calculation of systemic inflamatory index,systemic information response index and aggregate index of systemic inflamation ,and correlate these indices to SLE disease activity index

Correlation between hematologic indices in juvenile lupus erythematosus patients and disease activity in these patients

时间窗: 3-6 months

SLEDAI score in juvenile lupus erythematosus patients

次要结局

  • Calculation of chronic damage index in juvenile lupus erythematosus patients(3_6 months)
  • Relationship between hematologic index and chronic organ damage index in juvenile lupus erythematosus patients(3-6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Alshimaa Hamdey Khalaf

Assistant lecturer- Rheumatology and Rehabilitation department

Sohag University

研究点 (1)

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