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临床试验/CTRI/2020/06/026000
CTRI/2020/06/026000已完成不适用

Clinical Profile, management and outcomes of COVID-19 in kidney transplant recipients

Seth GS Medical College and KEM Hospital1 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2020年6月26日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
75
试验地点
1
主要终点
Outcome of kidney transplant recipients with Covid-19 infection

研究概览

简要总结

The worldwide spread of the Coronavirus disease 2019 (COVID-19) pandemic due to the novel SARS-CoV-2 virus, poses a significant challenge to the patients with chronic kidney disease. Especially renal transplant recipients are deemed to be more vulnerable, considering their state of immunosuppression. Solid organ transplant recipients may be at increased risk also as they have frequent contact with the health care system. Clinical features of COVID-19 among kidney recipients are not well documented but we know from our previous experience with infectious disease in this population that they can be dissimilar to those in nonimmunocompromised patients. Additional studies are required to determine the impact of specific immunosuppressive agents on the course of COVID-19 infection.Optimal management of COVID19 in kidney transplant recipients is not known and there is very scarce evidence about outcomes of COVID19 in kidney transplant recipients. We propose a retrospective observational study to evaluate the clinical profile, management and outcomes of COVID19 in kidney recipients. All recipients admitted to hospital with COVID19 will be enrolled in the study. Details of their demographics, presentation, investigations, treatment and outcome will be recorded from their files at the time of discharge or in an unfortunate event of death. There will be no extra investigation or cost for the purpose if the study.  The results of this study will fill the lacunae in the knowledge of presentation, management and outcomes of this disease. It will help us in improving our understanding of behavior of COVID19 in kidney transplant recipients which will enable us to better manage the patients in future.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • •Kidney transplant recipients admitted to KEMH with diagnosis of COVID-19 by investigation (Positive swab test for COVID-19)
  • •Age >18yrs
  • •Both genders are to be included.

排除标准

  • •Patients with incomplete medical records.

结局指标

主要结局

Outcome of kidney transplant recipients with Covid-19 infection

时间窗: 3 months

次要结局

  • 1.To find clinical, laboratory imaging features and course of disease(2. To study the response to therapy)

研究者

发起方
Seth GS Medical College and KEM Hospital
申办方类型
Research institution and hospital

研究点 (1)

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