Feasibility and metabolic effects of carbohydrate loading in patients with fragility hip fracture - a randomised double blind pilot study
Not Applicable
Completed
- Conditions
- Enhancement of recovery following hip fracture surgeryMusculoskeletal Diseases
- Registration Number
- ISRCTN91109766
- Lead Sponsor
- niversity of Nottingham (UK)
- Brief Summary
2014 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/25472724
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
1. Patients presenting through accident and emergency with a fragility neck of femur fracture requiring hemiarthroplasty
2. Aged 70 or over
3. Patients able to provide fully informed consent
Exclusion Criteria
1. Patients who are confused or unable to give their own consent
2. Patient known to suffer with diabetes (either type 1 or type 2)
3. Patients with current infections
4. Ongoing participation in another clinical trial
5. Multiple injuries requiring operative management
6. Previous intolerance to carbohydrate drinks
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oral glucose tolerance test; Timepoint(s): Day 1 post operation
- Secondary Outcome Measures
Name Time Method <br> 1. Glucose homeostasis - blood glucose; Timepoint(s): Blood glucose prior to induction of anaesthesia<br> 2. Blood glucose on day 1; Glucose homeostasis - insulin; Timepoint(s): Insulin concentration - prior to induction of anaesthesia, Insulin concentration - day 1 post op<br> 3. Length of acute hospital stay; Timepoint(s): Hospital discharge<br> 4. Mobility - Cumulated ambulation score; Timepoint(s): Days 1-3 post-op<br> 5. Muscle metabolism - muscle biopsy, contralateral leg; Timepoint(s): Prior to induction of anaesthesia At end of surgery<br> Day 1<br> 6. Nausea and vomiting; Timepoint(s): Prior to induction of anaesthesia Day 1 post-operation<br>