CTRI/2020/03/023957
招募中
未知
Prospective randomised trial for 6-months versus 9-months anti-microbial therapy for tubercular posterior uveitis
Hyderabad Eye Resesarch Foundation0 个研究点目标入组 0 人待定
概览
- 阶段
- 未知
- 干预措施
- 未指定
- 疾病 / 适应症
- 未指定
- 发起方
- Hyderabad Eye Resesarch Foundation
- 状态
- 招募中
- 最后更新
- 3年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •1\.Symptoms ï?£3 months
- •Objective evidence of active intraocular inflammation compatible with TPU
- •e.g. active retinal vasculitis (with FA leakage) or choroidal lesions
- •2\. Positive results of tuberculin skin test (TST, ï?³10 mm induration after 48 hours with 5TU) and/or interferon gamma release assay (Quantiferon TB Gold or T\-SPOT)
- •3\. May have evidence of healed pulmonary or other TB (but not requiring ATT for that disease)
- •4\. Age \>18 years, not pregnant or willing to use double contraception
排除标准
- •Ophthalmic findings or ancillary test results consistent with non\-TB diagnosis
- •Objective findings showing only non\-active disease eg. occluded retinal vessels only, with no FA leakage from non\-occluded vessels, or atrophic/scarred choroidal lesions
- •1\.Optic nerve involvement
- •2\.Past history of uveitis
- •3\.Previous ATT for ocular or other disease
- •4\.Concurrent active pulmonary or other TB disease requiring ATT for that disease.
- •5\.HIV infection and other immunocompromised patients
- •6\.Treated with systemic or local corticosteroids within 3 months prior to entry
- •7\.Received anti\-VEGF injections within 3 months prior to entry
- •8\.Age less than 18 years
结局指标
主要结局
未指定
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