Pilot trial of the Slider continuous positive airway pressure (CPAP) therapy prongs for use in neonates with respiratory distress syndrome

Not Applicable

• Conditions: Respiratory distress syndrome; Reproductive Health and Childbirth - Complications of newborn; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12622000577718
• Lead Sponsor: Melissa Weber

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-04-19
• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Neonates who are greater than 28 weeks gestational age who have been stable on conventional CPAP for 24 hours previously but still have respiratory distress syndrome requiring CPAP treatment.

Exclusion Criteria

Instability on CPAP requiring additional respiratory support or ventilation
Anatomical abnormalities impacting airway structure ie Cleft palate or Pierre Robin

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary objective of this study is to evaluate use of Slider prongs to deliver effective CPAP to preterm infants in infants requiring CPAP for respiratory distress. This is a composite primary outcome as the parameters of heart rate, saturation and presence of apnoeas will be assessed to determine if the CPAP delivery with the slider prongs is successful This is done with standard clinical monitoring equipment such as ECG leads and pulse oximetry.[ The trial participants will be assessed for the duration of their CPAP therapy and assessed using standard neonatal observations such as heart rate, respiratory rate, saturations and the presence or absence of apnoeas hourly for the duration of CPAP therapy]