Velopharyngeal sphincter morphology and function in healthy adults and patients with cleft lip and palate

• Conditions: Q37; Q35; Cleft palate with cleft lip; Cleft palate

• Registration Number: DRKS00005663
• Lead Sponsor: Forschungszentrum Jülich GmbH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-02-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Controls:
Body mass index (BMI) under 27, normal resonance

Arm/group 2 and 3 (Adult males with unilateral cleft lip and palate and adult females with cleft palate only): Body mass index (BMI) under 27

Exclusion Criteria

Controls:
MRI-Exclusioncriteria, cleft lip and palate, swallowing disorder, sleep apnea, muscleskelletal disorders, obesity

Arm/group 2 and 3 (Adult males with unilateral cleft lip and palate and adult females with cleft palate only):
MRI-Exclusioncriteria

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
enght, diameter, circumfence and angle of origin of the levator veli palatini muscle (LVP) and palatoglossus muscle (PG) measured by dynamic and static 3D MRI.