The Impacts of Different Stent Types in Acute Myocardial Infarction on the Risk of Atrial Fibrillation
试验速览
- 阶段
- 不适用
- 入组人数
- 40,000
- 主要终点
- new-onset atrial fibrillation
研究概览
简要总结
The benefit of a drug-eluting stent (DES) in patients with acute myocardial infarction (AMI) is controversial. This study will aim to observe the effect of a DES on the risk of new-onset AF in patients with AMI.
详细描述
Acute myocardial infarction (AMI) is the leading cause of mortality in the world. Early invasive strategy with percutaneous coronary intervention (PCI) has been demonstrated to be the most effective strategy to treat AMI. Although drug-eluting stent (DES) has not shown benefits to reduce mortality rate among AMI patients compared with bare-metal stent (BMS), the use of DES in real-world is increasing because of reduced restenosis rates. AMI patients are at higher risk to develop atrial fibrillation (AF) than general population. However, whether early PCI with DES implantation is related to a reduced risk of AF still remains unclear. The purpose of this study is to investigate the association of DES implantation and the risk of AF among patients with AMI treated by early PCI.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients were enrolled by primary diagnostic coding as acute myocardial infarction and treatment coding as receiving PCI between 2007 and 2013 in Taiwan National Health Insurance Research Database (NHIRD)
排除标准
- •Less than 20-years-old; Unknown sex and age
- •Not residents in Taiwan
- •Died during AMI admission
- •Previous history of AF
- •Receiving coronary artery bypass grafting (CABG), ventricular assist device (VAD), extracorporeal membrane oxygenation (ECMO), and heart transplantation during observational and/or database period
- •No stent implantation during PCI
- •Unknown stent types
结局指标
主要结局
new-onset atrial fibrillation
时间窗: one year
new record or diagnostic claims of atrial fibrillation after hospital discharge from acute myocardial infarction
次要结局
未报告次要终点
