Treatment of Children with All Stage of Hepatoblastoma with Temsirolimus(IND#122782, NSC#683864) Added to High Risk Stratum Treatment
- Conditions
- Hepatoblastoma
- Registration Number
- JPRN-UMIN000019840
- Lead Sponsor
- Children's Oncology Group
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 3
Not provided
1) Patients that have been previously treated with chemotherapy for hepatoblastoma or other hepatoblastoma-directed therapy 2)Any prior chemotherapy 3)Currently receiving another therapy with other investigational drug 4)Currently receiving another anticancer agents 5)Previously received a solid organ transplant 6) Uncontrolled infection 7) Pregnant or breast feeding 8) Childbearing potential, not practicing adequate contraception 9)Receiving corticosteroids 10)Receiving enzyme inducing anticonvulsants 11)Receiving CYP3A4 inducers or inhibitors 12)Receiving therapeutic anticoagulants 13)Receiving ACE inhibitors 14) Patients who have had a major surgical procedure within 6weeks prior to registration 15) Patient who is judged inappropriate to participate in this study by the investigators.(ex; Patients don't sign informed concent.)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method response rate at the end of 2nd cycle
- Secondary Outcome Measures
Name Time Method