Comparative research by means of skin prick test and provocation test between hypo allergenic Migo pear and Conference pear in patients with allergy to pear.
- Conditions
- allergyFood hypersensitivity1000170810016950
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
Signed informed consent form
18 years of age or older, mentally competent
Patients proven allergic to pear by skin prick test and prick to prick test
(HEP > 0,4)
Diet free of pear, earlier complaints after eating pear.
No use of antihistamines in the last 72 hours before the skin test and the food
challenge with pear.
Exclusion Criteria
Patiënt under 18 years, mentally incompetent.
Negative skin prick test and prick to prick test with pear (HEP < 0,4).
Diet not free of pear, eating pear without complaints.
Unable to stop beta blocker
Use of antihistamines in the last 72 hours before the skin prick test and food
challenge with pear
Use of more than 10 mg prednisone (relative contraindication)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Consuming the hypoallergenic Migo pear without experiencing an allergic<br /><br>reaction.</p><br>
- Secondary Outcome Measures
Name Time Method <p>2. How does the amount of pear, at which the patient experience symptoms,<br /><br>differ between the Migo pear and the Conference pear?<br /><br>3. What is the difference in surface area in the skin test between the Migo<br /><br>pear and the Conference pear?<br /><br>4. What is the difference in surface area in the skin test between the Migo<br /><br>pear and Birch pollen?</p><br>