Comparison of efficacy of intralesional vitamin D3 vs intralesional triamcinolone injection in the treatment of keloid

Not yet recruiting

• Conditions: Diseases of the musculoskeletal system and connective tissue,

• Registration Number: CTRI/2022/09/045800
• Lead Sponsor: SIKSHA O ANUSANDHAN UNIVERSITY

Brief Summary

This study is a randomized controlled trial  comparing the  safety and efficacy of intralesional triamcinolone versus intralesional vit D3 injection in the treatment of keloid . lesions will be assessed by clinical examination, VSS scale, digital photograph and visual analog scale for pain during treatment. Assessment will be done at baseline and every 3 weeks and 1 month after the last dose. The clinical improvement will be defined as decreasing values of the score and complete recovery  as  the score reach to zero. Scar flattening will be considered as <1mm scar height over 90% of the lesion.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-09-21
• Study Start: 2022-09-25

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• All patients with keloids above 18 years of age.
• patients having two or more than two keloids not more than 5cm 3.
• No treatment done for keloids in last 6 months.

Exclusion Criteria

• Pregnancy and lactation 2.
• Family history of keloids.
• Diabetes mellitus.
• 4.keloids on face.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Lesions will be assessed by clinical examination, Vancouver Scar Scale (VSS), digital photograph and Visual Analogue Scale for pain during treatment.	Assessment will be done at baseline and every 3 weeks and 1 month after last dose.

Secondary Outcome Measures

Name	Time	Method
The clinical improvement will be defined as decreasing values of the scores and complete recovery as scores reach to zero.	Scar flattening will be consired as 1mm scar height over 90% of the lesion

Trial Locations

Locations (1)

IMS AND SUM HOSPITAL; 🇮🇳 Khordha, ORISSA, India

IMS AND SUM HOSPITAL

🇮🇳Khordha, ORISSA, India

Bikash Ranjan Kar

Principal investigator

9937428181

karbikash@gmail.com