Evaluation of Right Ventricular Systolic Function by TAPSE Parameter From Subcostal View

• Conditions: Transthoracic Echocardiography
• Interventions: Diagnostic Test: Transthoracic echocardiography

• Registration Number: NCT04490538
• Lead Sponsor: Emergency Medical Service of the Central Bohemian Region, Czech Republic

Brief Summary

The purpose of this study is to validate a new echocardiographic parameter evaluating right ventricular function.

Detailed Description

The key conventional echocardiographic parameter evaluating right ventricular systolic function is the tricuspid annular plane systolic excursion (TAPSE). It is measured in apical four chamber view by conventional M-mode imaging. Other echocardiographic parameters of right ventricular systolic function (Fractional Area Change; Tricuspid Lateral Annular Systolic Velocity; Right Ventricular Index of Myocardial Performance) are evaluated in apical four chamber view as well. However, this view might not be clearly visible in the clinical setting of critical illness and subcostal view is often preferred for its higher quality. Unfortunately, conventional M-mode can not be used for measurement in this view but anatomical M-mode imaging can. Therefore, the investigators decided to evaluate whether TAPSE measured in subcostal view by anatomical M-mode (sTAPSE) correlates with conventional TAPSE and whether reliably reflects systolic right ventricular function.

Study Timeline

• Study First Submitted: 2020-07-19
• Study First Submitted QC: 2020-07-26
• Study Start: 2020-07-27
• Study First Posted: 2020-07-29
• Status Verified: 2020-08
• Last Update Submitted: 2020-08-18
• Last Update Posted: 2020-08-19
• Primary Completion: 2020-09-30
• Study Completion: 2020-10-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Inpatients
• All patients hospitalised in intensive care unit indicated for transthoracic echocardiography examination

Exclusion Criteria

• Age <18 years
• Insufficient imaging quality of transthoracic echocardiography
• Refusal of echocardiographic examination by patient

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Critically ill patients	Transthoracic echocardiography	Critically ill patients hospitalised at the intensive care unit indicated to echocardiographic examination.

Primary Outcome Measures

Name	Time	Method
Validity of sTAPSE in prediction of right ventricular systolic dysfunction	During the intervention	sTAPSE is a new potential echocardiographic parameter of right ventricular systolic function measurable from subcostal view.

Secondary Outcome Measures

Name	Time	Method
Correlation of sTAPSE with conventional TAPSE	During the intervention	sTAPSE is a new potential echocardiographic parameter of right ventricular systolic function measurable from subcostal view.

Trial Locations

Locations (1)

Masaryk Hospital Usti nad Labem; 🇨🇿 Usti nad Labem, Czechia