ROSCAP: Reduction of Smoking in Cardiac Patients Study

Not Applicable

Completed

• Conditions: Nicotine Dependence; Tobacco Dependence; Cardiac Disease

• Registration Number: NCT00301626
• Lead Sponsor: National Institutes of Health (NIH)

Brief Summary

Background. The ROSCAP Study was a randomized controlled trial in heart disease patients to test the effect of a smoking reduction intervention on cigarettes per day (cpd) and biochemical and clinical indicators of tobacco exposure. .

Detailed Description

Not available

Study Timeline

• Study Start: 2000-10
• Study Completion: 2005-01
• Status Verified: 2005-04
• Study First Submitted: 2006-03-10
• Study First Submitted QC: 2006-03-10
• Study First Posted: 2006-03-13
• Last Update Submitted: 2008-10-23
• Last Update Posted: 2008-10-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

• smoked at least 15 cigarettes per day and had one of 11 cardiovascular disorders: history of myocardial infarction, coronary artery bypass surgery, angioplasty, stent placement, thrombolytic therapy, angina, arrhythmia, a history of cardiac arrest, greater than 50% coronary artery stenosis by angiography, ischemia on exercise tolerance testing or congestive heart failure, required to confirm that they were unwilling or uninterested in setting a stop smoking date in the next 30 days.

Exclusion Criteria

• 1. unstable angina within the past 2 weeks, 2) unstable psychiatric or substance use disorders or 3) contraindications to nicotine replacement therapy (including pregnancy or intention to become pregnant)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Smoking reduction

Secondary Outcome Measures

Name	Time	Method
Smoking cessation, biomarker measures

Trial Locations

Locations (1)

Minneapolis VAMC (111-0); 🇺🇸 Minneapolis, Minnesota, United States