The effect of low dose tolvaptan after cardiovascular surgery
Not Applicable
Recruiting
- Conditions
- after cardiovascular surgery associated with cardiopulmonary bypass
- Registration Number
- JPRN-UMIN000033992
- Lead Sponsor
- Kobe City Medical Center General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 240
Inclusion Criteria
Not provided
Exclusion Criteria
Urgency or emergency operation CKD (dialysis, eGFR<30) Heart failure with EF<40% Heart failure or infection within preoperative 4 weeks Thoracoabdominal aortic replacement surgery and OPCAB Artificial respiration management over 24 hours and reintroduction Tolvaptan allergy Without feeling dry mouth or water ingestion Hypernatremia Patients with pregnant, possibility of pregnancy and pregnancy wish Using tolvaptan preoperatively
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Whether returning to the target weight by the 6th postoperative day
- Secondary Outcome Measures
Name Time Method worsening renal function, urine volume / body weight