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Clinical Trials/NCT03986164
NCT03986164
Completed
N/A

Implants Immediately Installed in Esthetic Area With Computer-guided Surgery: Randomized Clinical Trial

University of Campinas, Brazil1 site in 1 country40 target enrollmentApril 10, 2019
ConditionsDental Implants

Overview

Phase
N/A
Intervention
Not specified
Conditions
Dental Implants
Sponsor
University of Campinas, Brazil
Enrollment
40
Locations
1
Primary Endpoint
Position of the implant
Status
Completed
Last Updated
last year

Overview

Brief Summary

The objective of this randomized and longitudinal clinical study is to compare the installation of immediate implants in the esthetic zone through computer-guided-surgery and conventional surgery. To this end, 22 patients who need implant-supported replacement on the anterior region of the maxilla will be selected and after extraction will receive: Guided surgery (GS): installation of dental implant with the aid of the virtually planned guide by means of specific software; Conventional surgery (CS): installation of dental implant performed freehand using a conventional surgical guide made by study models.

Detailed Description

The objective of this randomized and longitudinal clinical study is to compare the installation of immediate implants in the esthetic zone through computer-guided-surgery and conventional surgery. To this end, 22 patients who need implant-supported replacement on the anterior region of the maxilla will be selected and after extraction will receive: Guided surgery (GS): installation of dental implant with the aid of the virtually planned guide by means of specific software; Conventional surgery (CS): installation of dental implant performed freehand using a conventional surgical guide made by study models. Tomographies will be performed 10 days after the surgery for the measurement of both linear and angular shifts between the installed implants and the virtual planning. All the clinical and radiographic assessments (Plaque and Bleeding Index, Drilling Depth, Relative Clinical Insertion Level and the Margin Position of Peri-Implant Mucosa) will be carried out after the surgery and within 6 and 12 months of post-operative. Assesments of the esthetic success (pink/white score) and survival and success of the implant will also be carried out. In the prosthetic part, it will be assessed the abutment mobility; corrective measures for the prothesis; repair on prothesis or abutment. The success and survival assessments of crowns will be done through structure fracture, occlusal roughness, marginal integrity and contour of the restoration. It will also be assessed the procedural impact in quality of life by applying a 36-closed-question-survey focused on appearence, pain, oral comfort, general performance, feeding and chewing. Subsequently, the data will be tabulated, and according to their distribution, the appropriate statistical tests will be applied, considering a 5% index of significance to all the analyses.

Registry
clinicaltrials.gov
Start Date
April 10, 2019
End Date
February 28, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University of Campinas, Brazil
Responsible Party
Principal Investigator
Principal Investigator

Enilson Antonio Sallum

Full professor, department of Periodontics, Piracicaba Dental School, State University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil

University of Campinas, Brazil

Eligibility Criteria

Inclusion Criteria

  • Patients with sufficient bone volume availability apically and palatally that allows the correct positioning of the implants (Kan et al, 2011);
  • Implants with primary stability of 20-45 N (Gallucci et al, 2014);
  • Patients with teeth to be extracted in the Class I, II or III corono-radicular position, according to Kan et al. (2011);
  • Patients with distance from the bone crest to the point of contact in adjacent teeth less than or equal to 6.5mm (Buser et al 2017).

Exclusion Criteria

  • Presence of diabetes, blood disorders and systemic diseases that prevent the surgical procedure;
  • History of radiotherapy in the head or neck region;
  • History of treatment with bisphosphonates;
  • Pregnant or lactating women;
  • Patients with teeth to be extracted in the Class V corono-radicular position, according to Kan et al. (2011);
  • Gingival recession in the teeth indicated for exodontia (Kan et al, 2001);
  • Acute infection at the implant site (Morton et al, 2014);
  • Unavailability to attend the FOP / UNICAMP on the pre-determined days.

Outcomes

Primary Outcomes

Position of the implant

Time Frame: Baseline, 10 days

Difference between angular position of the implant by computer software and angular position of the implant by free hand.

Secondary Outcomes

  • Peri-implant probing depth(Immediately after surgery, 6 months, 12 months)
  • Relative gingival margin position(Immediately after surgery, 6 months, 12 months)
  • Relative clinical attachment level(Immediately after surgery, 6 months, 12 months)

Study Sites (1)

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