The effect of licorice and ginger herbal composition on controlling patients' pain symptoms after knee joint replacement surgery

Phase 1

• Conditions: Osteoarthritis, Total knee arthroplasty (TKA), Pain after surgery.; Unilateral primary osteoarthritis, unspecified knee; M17.10

• Registration Number: IRCT20080901001165N62
• Lead Sponsor: Bagheiat-allah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 July 2020

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients are candidates for complete knee replacement after surgery and hospital discharge

Exclusion Criteria

Inflammatory underlying disease such as rheumatoid arthritis
Drug addiction
smoking

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of the effect of different doses of licorice and ginger herbal composition in one group and diclofenac drug in the second group. Timepoint: Before the intervention, and 8, 12 and 24 hours after consuming the herbal combination, licorice and ginger, every 12 hours to 8 weeks. Method of measurement: The pain VAS is a unidimensional measure of pain intensity.

Secondary Outcome Measures

Name	Time	Method
Post-intervention Quality of life score. Timepoint: Up to 28 weeks after the intervention. Method of measurement: It will be measured according to the Cop Corn questionnaire.