The Proton Pump Inhibitor (PPI) Test for the Extraesophageal Manifestation of GERD
Not Applicable
- Conditions
- Gastroesophageal Reflux Disease
- Registration Number
- NCT00539786
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
PPI test;empirical trial with high-dose proton-pump inhibitors (PPIs) has been shown to be a sensitive tool for diagnosing patients with GERD. However, this diagnostic strategy has not been well established in patients with extraesophageal manifestation of GERD. In this study, we aim to see the relevance of PPI test in diagnosing GERD in patients with extraesophageal symptoms.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- Patients with extraesophageal manifestation symptoms of GERD
Exclusion Criteria
- laryngeal, pharyngeal, liver, lung, renal, or hematological disorders
- a history of gastrointestinal surgery, and a history of connective tissue disorders.
- patients with duodenal or gastric ulcers as well as other significant lesions, such as gastric cancer, esophageal cancer, or subepithelial tumors more than 1 cm observed on the upper endoscopy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Symptom responders after PPI trials 2 weeks after PPI trials
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Samsung Medical Center, Sungkyunkwan University School of Medicine
🇰🇷Seoul, Gangnam-gu, Korea, Republic of