Assessing the effectiveness of Homoeopathic Medicines Croton tiglium and Lycopodium clavatum in the treatment of Irritable Bowel Syndrome- An Open Label Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
研究概览
简要总结
Irritable Bowel Syndrome(IBS) is a functional bowel disorder in the absence of detectable structural abnormalities. There is no clear diagnostic markers for IBS. Thus, the diagnosis is based on history and clinical presentation.
Symptoms of the condition include abdominal pain, diarrhea, constipation, mucus discharge per rectum and altered stool appearance. The genesis of disease is complex with multiple factors contributing to its occurrence. Cause of IBS is not fully known, but biopsychosocial variables are likely to play an essential role, along with luminal factors such as diet and the gut flora.
A complex combination of components, including psychological stress, hormones, the immune system and neurotransmitters appear to disrupt communication between the brain and the gut. The prevalence of Irritable Bowel Syndrome in Western countries ranges from 4-5%., in Asian countries 1-10% and in India prevalence is estimated at 4-7.9%. The prevalence in North India is 4%.
Irritable Bowel Syndrome is a multifactorial disorder and it should be treated by considering various factors including mental status of the patient. Homoeopathy is a viable therapeutic option, since it takes into account diseased individual rather than disease- a holistic approach which includes various factors like mode of living, habits, occupation, mind and disposition along with the physical symptoms.
Homoeopathic medicines like Croton tiglium and Lycopodium clavatum, which were well proved and documented in source books. There are different literature shows that Lycopodium clavatum is well indicated for Irritable Bowel Syndrome. The action of Croton tiglium on gastrointestinal system is, it alters the bowel habits by affecting contractile frequency and amplitude of intestinal smooth muscles. Hence, this study is intended to assess and compare the effectiveness of these two medicines in the treatment of Irritable Bowel Syndrome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 21.00 Year(s) 至 45.00 Year(s)(—)
- 性别
- All
入选标准
- •Subjects who are voluntarily willing to take part in this study and sign the written informed consent Subjects between age group of 21 to 45 years Diagnosed new cases of Irritable Bowel Syndrome using the Rome IV criteria.
排除标准
- •Subjects having alarming features like anemia, unintended weight loss, nocturnal diarrhea, blood in stool, persistent diarrhea Subjects with systemic illness Subjects with severity scoring system greater than or equal to 300 Pregnant and Lactating women.
研究者
Dr Pralhad
Government Homoeopathic Medical College and Hospital
