Prevention of bone loss following spinal cord injury

Completed

• Conditions: Musculoskeletal Diseases: Osteoporosis; Musculoskeletal Diseases; Osteoporosis without pathological fracture

• Registration Number: ISRCTN46977778
• Lead Sponsor: Record Provided by the NHSTCT Register - 2004 Update - Department of Health (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2004-09-30
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

1. Patients admitted to Royal National Orthopaedic Hospital (RNOH) with a spinal cord injury

Added 16/04/10:
2. Female patients had to be postmenopausal, surgically sterile or willing to practice a medically acceptable form of birth control during the study period and for at least 12 months after study completion
3. All subjects gave written consent to take part in the study

Exclusion Criteria

Added 16/04/10:
1. Pregnant or breastfeeding
2. Previous history of allergic reaction to bisphosphonates
3. Previous history of iritis or uveitis
4. Significant renal impairment or evidence of vitamin D deficiency (serum 25-hydroxyvitamin D <25 nmol/L)

Study & Design

• Study Type: Interventional
• Study Design: Not specified