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Procedural Complications and Long-Term Mortality in Complex Coronary Interventions

Not yet recruiting
Conditions
Complex Coronary Artery Disease
Registration Number
NCT07202754
Lead Sponsor
Istanbul Mehmet Akif Ersoy Educational and Training Hospital
Brief Summary

The relative risks for different non-fatal intraprocedural complications during complex percutaneous coronary intervention (PCI) on subsequent mortality have not been described. This study aimed to assess the association between non-fatal intraprocedural complications and late mortality after complex coronary PCI.

Detailed Description

Complex coronary lesions include chronic total occlusion, osteal epicardial lesions, long (diffuse) coronary disease, severe calcific lesions, true bifurcation disease, left main coronary lesion, lesions with severe thrombus, and in-stent restenosis. Non-fatal intraprocedural complications included abrupt occlusion, worsening of thrombolysis in myocardial infarction (TIMI) flow grade (TIMI \< 3), major dissection (greater than type B), occurrence of thrombus formation, perforation of the main vessel or side branch, malignant arrhythmias, stroke/transient ischemic attack, and non-coronary major bleeding.

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
20000
Inclusion Criteria
  • Patients with complex coronary disease
  • Aged 18-85 years
Exclusion Criteria
  • Patients diagnosed with cardiogenic shock
  • Coronary lesions with non-complex features
  • Percutaneous coronary intervention with a bare metal stent
  • Patient life expectancy <1 year
  • Known relevant allergies
  • Absence of all medical records
  • Patients with early discontinuation of dual antiplatelet therapy

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Deathup to 60 months

All cause death

Secondary Outcome Measures
NameTimeMethod

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