NCT07667829尚未招募不适用
Comparison of the Efficacy and Safety of Dopamine, Norepinephrine and Epinephrine in the Treatment of Pulmonary Hypertensive Crisis Under Hemodynamic Monitoring
China National Center for Cardiovascular Diseases3 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2026年6月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 75
- 试验地点
- 3
研究概览
简要总结
Comparison of the efficacy and safety of three vasoactive agents-dopamine, norepinephrine, and epinephrine-in the treatment of patients with pulmonary hypertension crisis: prospective, randomised controlled trial monitored by haemodynamic monitoring
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years old;
- •Signed informed consent form;
- •Confirmed diagnosis of arterial pulmonary hypertension (PAH) and/or chronic thromboembolic pulmonary hypertension (CTEPH);
- •Presenting with manifestations of pulmonary hypertensive crisis;
- •Receiving both diagnosis and treatment in-hospital;
- •No intravenous administration of the vasopressor drugs (including dopamine, norepinephrine, and epinephrine) under study at enrollment.
排除标准
- •At SCAI stage D or stage E ;
- •Patients who only receive a diagnosis but no treatment in the hospital;
- •Uncontrolled hyperthyroidism;
- •Complicated with angle-closure glaucoma;
- •Hypersensitivity to the study drug;
- •Ongoing use of halogenated hydrocarbon general anesthetics such as cyclopropane and halothane;
- •Ongoing use of monoamine oxidase inhibitor (MAOI) antidepressants or anti-Parkinson drugs (phenelzine, tranylcypromine, isocarboxazid, moclobemide);
- •Already receiving the vasopressor drugs (dopamine, norepinephrine, epinephrine) under study at enrollment.
研究者
Qing Gu
Study Chair
Chinese Academy of Medical Sciences, Fuwai Hospital
研究点 (3)
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