Effects of Short-Term Olive Leaf Extract Supplementation in Elite Male Handball Players
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Karabuk University
- Enrollment
- 18
- Locations
- 1
- Primary Endpoint
- Muscle Soreness
Overview
Brief Summary
Olive leaf extract (OLE) is a natural supplement rich in phenolic compounds, especially oleuropein, which has antioxidant properties that may support recovery after physical exercise. While OLE has been studied for various health-related effects, its potential impact on exercise recovery and performance in elite athletes remains unclear.
This randomized, double-blind, placebo-controlled study was designed to evaluate the effects of four weeks of OLE supplementation on physical performance, sleep quality, and post-exercise muscle soreness in elite male handball players aged 18 to 25 years. Participants were randomly assigned to receive either a daily OLE supplement (500 mg, standardized to 25% oleuropein) or a placebo for four weeks. Physical performance, sleep quality, and muscle soreness were assessed at baseline, during the intervention, and at the end of the study period. Muscle soreness was additionally evaluated at 12 and 24 hours following exercise sessions.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Triple (Participant, Care Provider, Investigator)
Masking Description
double blind (participant investigator)
Eligibility Criteria
- Ages
- 18 Years to 25 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Male elite handball players aged 18 years or older
- •Free from any diagnosed chronic disease, as determined by medical history
- •Not following a calorie-restricted diet within the previous six months
- •No use of nutritional supplements within the previous six months
Exclusion Criteria
- •Age under 18 years
- •Smoking or alcohol consumption
- •Presence of any diagnosed chronic disease
- •Adherence to a regular calorie-restricted diet within the previous six months
- •Use of nutritional supplements during the previous six months
Arms & Interventions
Study group
olive leaf extract supplemented
Intervention: Olive leaf extract (Dietary Supplement)
Control group
placebo capsule supplemented
Intervention: Placebo (Other)
Outcomes
Primary Outcomes
Muscle Soreness
Time Frame: Baseline, After intervention (two week later), After intervention (fourt week later)
The severity of muscle soreness will be assessed using the Visual Analog Scale (VAS). Patients choose the appropriate score between 0 and 10. Higher scores indicate higher muscle soreness levels.
Squat jump height
Time Frame: Performance outcomes were assessed at baseline, week 2, and week 4 of the intervention period.
Lower-body explosive performance was assessed using the squat jump test. Jump height was measured in centimeters (cm) with higher values indicating better explosive performance.
Peak anaerobic power
Time Frame: baseline, week 2, and week 4.
Peak anaerobic power was assessed using the Wingate anaerobic test. Peak power output was recorded in watts (W) during the 30-second maximal cycling test. Higher values indicate greater anaerobic power.
Countermovement jump height
Time Frame: Assessments were conducted at baseline, week 2, and week 4. Higher values indicate better explosive performance.
Lower-body explosive performance was assessed using the countermovement jump test. Jump height was measured in centimeters (cm) with higher values indicating better explosive performance.
Mean anaerobic power
Time Frame: Baseline, week 2, and week 4
Mean anaerobic power was assessed using the Wingate anaerobic test. Mean power output was calculated as the average power produced over the 30-second test and recorded in watts (W). Higher values indicate better anaerobic capacity.
Fatigue index
Time Frame: Baseline, week 2, and week 4
Fatigue index was assessed using the Wingate anaerobic test and calculated as the percentage decline in power output from peak to minimum power during the 30-second test. Higher values indicate greater fatigue.
Secondary Outcomes
- Sleep quality(Total PSQI scores were recorded at baseline, week 2, and week 4 to evaluate changes in perceived sleep quality during the supplementation period.)
Investigators
Büşra Demirer
Dr. Research Assistant, Nutritients
Karabuk University