Checking of response to inhaled corticosteroid treatment on a new laboratory parameter (blood CD28) in patients of asthma
Not Applicable
Completed
- Conditions
- Health Condition 1: J454- Moderate persistent asthma
- Registration Number
- CTRI/2015/07/005977
- Lead Sponsor
- ady Hardinge Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
Diagnosed patients of bronchial asthma of mild to moderate severity who will be started on inhaled corticosteroids according to standard treatment of care.
Exclusion Criteria
Pregnancy
Smoking
Acute severe asthma
patients who have taken corticosteroids in any form in last 4 weeks
patients with any other co-existent and active pulmonary infection
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of serum CD28 levels in asthmatic patients with healthy adults <br/ ><br>Change in serum levels of CD28 in asthmatic patients after treatment with inhaled corticosteroidsTimepoint: 4 weeks
- Secondary Outcome Measures
Name Time Method Correlation between asthma severity score as measured by SOA questionnaire and CD28 level <br/ ><br>Change in quality of life scores in asthma as measured by QOLtech AQLQ questionnaire, after treatment with inhaled corticosteroidsTimepoint: 4weeks