A Phase III Study of the Efficacy of Taxotere/Aptosyn Versus Taxotere/Placebo in Non-Small Cell Lung Cancer Patients
- Conditions
- Non-Small Cell Lung Cancer
- Registration Number
- NCT00085826
- Lead Sponsor
- Astellas Pharma Inc
- Brief Summary
Taxotere has been approved by the FDA and is considered a standard treatment for patients with lung cancer who have failed prior platinum-containing regimens. The main purpose of this research study is to determine if Aptosyn, when given in combination with Taxotere, will result in prolonged survival when compared to Taxotere alone.
This study will also help determine tumor response rates, and the safety profile of Aptosyn in combination with Taxotere.
This study has been completed and a publication is pending.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Not specified
- Target Recruitment
- 600
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (96)
Oncology-Hematology Associates
🇺🇸Pittsburgh, Pennsylvania, United States
Temple Cancer Center
🇺🇸Philadelphia, Pennsylvania, United States
The Texas Cancer Center - Dallas Southwest
🇺🇸Dallas, Texas, United States
Texas Oncology, P.A
🇺🇸Arlington, Texas, United States
Central Maryland Oncology Center
🇺🇸Columbia, Maryland, United States
Waco Cancer Care & Research Center
🇺🇸Waco, Texas, United States
Pacific Coast Hematology/Oncology Medical Group, Inc.
🇺🇸Fountain Valley, California, United States
California Cancer Care, Inc.
🇺🇸Greenbrae, California, United States
Scripps Cancer Center
🇺🇸SanDiego, California, United States
Redwood Regional Medical Group
🇺🇸Santa Rosa, California, United States
Evanston Northwestern Healthcare
🇺🇸Evanston, Illinois, United States
Northwest Medical Specialists, PC
🇺🇸Niles, Illinois, United States
Hematology Oncology Associates of Illinois
🇺🇸Skokie, Illinois, United States
Onc/Hem Associates of Central Illinois
🇺🇸Peoria, Illinois, United States
Iowa Cancer Care, PLC
🇺🇸Cedar Rapids, Iowa, United States
Iowa Oncology Associates
🇺🇸Cedar Rapids, Iowa, United States
The Center for Cancer Care & Research
🇺🇸St. Louis, Missouri, United States
Raleigh Hematology Oncology Clini
🇺🇸Cary, North Carolina, United States
Northeastern Carolina Hematology & Oncology, PA
🇺🇸Hickory, North Carolina, United States
Raleigh Hematology Oncology Clinic
🇺🇸Raleigh, North Carolina, United States
Medical Oncology Associates of Wymoning Valley, PC
🇺🇸Kingston, Pennsylvania, United States
Thomas Jefferson University Hospital
🇺🇸Philadelphia, Pennsylvania, United States
Hematology & Oncolgy Assoc of NE PA
🇺🇸Dunmore, Pennsylvania, United States
Texas Oncology, PA
🇺🇸Irving, Texas, United States
Cancer Care Associates
🇺🇸Tulsa, Oklahoma, United States
Dayton Oncology/Hematology, PA
🇺🇸Kettering, Ohio, United States
Texas Cancer Center at Medical City
🇺🇸Dallas, Texas, United States
Texas Onclology, PA
🇺🇸Dallas, Texas, United States
Texas Oncology, P.A.
🇺🇸Bedford, Texas, United States
Texoma Cancer Center
🇺🇸Wichita Falls, Texas, United States
Texas Cancer Center
🇺🇸Ft. Worth, Texas, United States
Texas Cancer Center of Mesquite
🇺🇸Mesquite, Texas, United States
Allison Cancer Center
🇺🇸Midland, Texas, United States
West Texas Cancer Center
🇺🇸Odessa, Texas, United States
San Antonio Tumor and Blood Clinic
🇺🇸Fredicksburg, Texas, United States
Tyler Cancer Center
🇺🇸Tyler, Texas, United States
Deke Slayton Cancer Center
🇺🇸Webster, Texas, United States
Virginia Oncology Associates
🇺🇸Norfolk, Virginia, United States
Fairfax Northern Virginia Hematology-Oncology, PC
🇺🇸Fairfax, Virginia, United States
Washington Cancer Center, P.C.Puget Sound Cancer Cente
🇺🇸Seattle, Washington, United States
Cancer Care Northwest
🇺🇸Spokane, Washington, United States
MultiCare Health System
🇺🇸Tacoma, Washington, United States
Northwest Cancer Specialists, PC
🇺🇸Vancouver, Washington, United States
Minnesota Oncology Hematology, PA
🇺🇸St. Paul, Minnesota, United States
12. Rocky Mountain Cancer Centers-Englewood
🇺🇸Englewood, Colorado, United States
Rocky Mountain Cancer Center
🇺🇸Boulder, Colorado, United States
Rocky Mountain Cancer Centers
🇺🇸Thornton, Colorado, United States
Arizona Clinical Research Center
🇺🇸Tucson, Arizona, United States
Impath Predictive Oncology
🇺🇸Franklin, Massachusetts, United States
Central Maryland Oncology Group
🇺🇸Towson, Maryland, United States
Missouri Cancer Associates
🇺🇸Columbia, Missouri, United States
New York Oncology Hematology, PC
🇺🇸Albany, New York, United States
New Mexico Cancer Center Associates
🇺🇸Santa Fe, New Mexico, United States
New York Oncology Hematology
🇺🇸Albany, New York, United States
Cancer Research of Long Island
🇺🇸Great Neck, New York, United States
HemOnCare, PC
🇺🇸Brooklyn, New York, United States
Asheville Hematology & Oncology Associates, PA
🇺🇸Asheville, North Carolina, United States
North Shore Hematology/Oncology Associates, P.C.
🇺🇸East Setauket, New York, United States
Willamette Valley Cancer Center
🇺🇸Eugene, Oregon, United States
Mamie McFadden Ward Cancer Center
🇺🇸Beaumont, Texas, United States
US Oncology Research
🇺🇸Dallas, Texas, United States
Lake Vista Cancer Center
🇺🇸Lewisville, Texas, United States
Puget Sound Cancer Centers
🇺🇸Edmonds, Washington, United States
Ranier Oncology Professional Services
🇺🇸Puyallup, Washington, United States
Oncology & Hematology Associates of South West Virginia, Inc.
🇺🇸Salem, Virginia, United States
Birmingham Hematology Oncology Associates
🇺🇸Birmingham, Alabama, United States
Birmingham Hematology and Oncology Associates, LLC
🇺🇸Birmingham, Alabama, United States
RMCC
🇺🇸Denver, Colorado, United States
Sharp Clinical Oncology Research
🇺🇸San Diego, California, United States
Cancer Centers of Florida
🇺🇸Orlando, Florida, United States
Central Indiana Cancer Centers
🇺🇸Indianapolis, Indiana, United States
Regional Hamatology Oncology Associates
🇺🇸Durham, North Carolina, United States
Piedmont Hematology Onccology Associates, P.A.
🇺🇸Winston-Salem, North Carolina, United States
Cancer Care Associates - Baptist Campus
🇺🇸Oklahoma City, Oklahoma, United States
an Antonio Tumor and Blood Clinic
🇺🇸San Antonio, Texas, United States
Hematology Oncology Associates of South Texas
🇺🇸San Antonio, Texas, United States
Utah Cancer Specialists
🇺🇸Salt Lake City, Utah, United States
Kansas City Oncology and Hematology Group
🇺🇸Kansas City, Missouri, United States
Lauderhill Lakes
🇺🇸Plantation, Florida, United States
Hematology & Oncology Associates
🇺🇸Phoenix, Arizona, United States
Hematology Oncology Centers of the Northern Rockies
🇺🇸Billings, Montana, United States
Cancer Centers of the Carolinas
🇺🇸Greenville, South Carolina, United States
Boca Raton Comprehensive Cancer Center
🇺🇸Boca Raton, Florida, United States
Northern Arizona Hematology and Oncology Associates
🇺🇸Flagstaff, Arizona, United States
Comprehensive Cancer Care Specialists at Boca Raton
🇺🇸Boca Raton, Florida, United States
Florida Cancer Institute
🇺🇸New Port Richey, Florida, United States
Ocala Oncology Center
🇺🇸Ocala, Florida, United States
University of Tennessee Cancer Institute
🇺🇸Memphis, Tennessee, United States
Florida Oncology Associates
🇺🇸Orange Park, Florida, United States
South Austin Cancer Center
🇺🇸Austin, Texas, United States
Interlakes Oncology & Hematology, P.C.
🇺🇸Rochester, New York, United States
University of Wisconsin Comprehensive Cancer Center
🇺🇸Madison, Wisconsin, United States
Arkansas Oncology Associates, PA
🇺🇸Little Rock, Arkansas, United States
North Florida Hematology & Oncology Association
🇺🇸Jacksonville, Florida, United States
Northern Arizona Hematology & Oncology Associates
🇺🇸Sedona, Arizona, United States
South Florida Oncology & Hematology Consultants
🇺🇸Lauderhill, Florida, United States