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Clinical Trials/ISRCTN85278228
ISRCTN85278228
Completed
Phase 2

Improving depression treatment outcomes by better repairing positivity deficits: A Feasibility pilot randomised controlled trial evaluation of an Augmented Depression Therapy targeting wellbeing (ADepT)

niversity of Exeter0 sites82 target enrollmentMarch 27, 2017

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Not specified
Sponsor
niversity of Exeter
Enrollment
82
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

2019 Protocol article in https://doi.org/10.1186/s40814-019-0438-1 (added 29/03/2021) 2023 Results article in https://doi.org/10.1016/j.eclinm.2023.102084 (added 17/07/2023)

Registry
who.int
Start Date
March 27, 2017
End Date
January 1, 2020
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity of Exeter

Eligibility Criteria

Inclusion Criteria

  • 1\. Aged over 18 or over
  • 2\. Suffering from a current major depressive episode (MDE) assessed by structured clinical interview for diagnosis (SCID\-I)
  • 3\. Have a Patient Health Questionnaire (PHQ\-9\) depression score \=\>10
  • 4\. Present with significant anhedonic symptoms (PHQ\-9 item 1 score \=\>2\)

Exclusion Criteria

  • 1\. Depression is not the primary presenting problem
  • 2\. Alcohol or drug dependent
  • 3\. Acutely suicidal or self\-harming
  • 4\. Cognitively impaired
  • 5\. Have bipolar disorder or psychosis/psychotic symptoms ascertained at baseline research interviews
  • 6\. Currently receiving another psychological therapy

Outcomes

Primary Outcomes

Not specified

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