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临床试验/NCT07242027
NCT07242027已完成不适用

Lactate-to-albumin, CRP-to-albumin and Procalcitonin-to-albumin Ratios Predict Mortality in Critically Ill Adults: a Retrospective ICU Cohort Study

Medical University of Silesia1 个研究点 分布在 1 个国家目标入组 212 人开始时间: 2025年3月21日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
212
试验地点
1
主要终点
In-hospital mortality

研究概览

简要总结

This observational study aims to determine whether three blood test ratios - lactate-to-albumin, CRP-to-albumin, and procalcitonin-to-albumin - can predict in-hospital mortality among critically ill adults. The study includes all adult patients admitted in 2024 to the ICU Ward B at the Silesian Center for Heart Diseases (SCCS) in Zabrze. Researchers will analyze retrospective clinical and laboratory data from electronic medical records, including lab values collected at ICU admission, patient demographics, diagnoses, and outcomes. The biomarker ratios will be manually calculated in Excel and statistically evaluated. The main goal is to assess whether these ratios are associated with patient survival and to identify predictive cut-off values to support early risk stratification in the ICU setting.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥ 18 years
  • Admission to ICU in 2024
  • Availability of data for lactate, CRP, procalcitonin, and albumin

排除标准

  • Missing outcome data (e.g. unknown survival status)
  • Lack of laboratory parameters necessary for ratio calculation

结局指标

主要结局

In-hospital mortality

时间窗: 100 days from the date of ICU admission

All-cause in-hospital mortality among ICU patients during the index hospitalization.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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