Effects of Chemotherapy on Perceived Daily Performance and Executive Functions of Adults With Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- Change in scores of Canadian Occupational Performance Measure.
研究概览
简要总结
The purpose of this study is to examine changes in perceived daily performance and executive functioning following chemotherapy in individuals with non-central nervous system cancers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Newly diagnosed with a primary non-central nervous system malignancy (lung, breast, colon, ulcer, urinary tract, canine tumors).
- •Stages I-III.
- •Pre-commencement of adjuvant (post-surgery) or neoadjuvant (prior to surgery) chemotherapy.
- •Understand and read Hebrew.
- •Have at least 12 years of education.
排除标准
- •Diagnosed with central nervous system malignancies.
- •Had a previous malignancy.
- •Have or had metastatic disease.
- •Have a history of a neurological condition or severe depression.
结局指标
主要结局
Change in scores of Canadian Occupational Performance Measure.
时间窗: Change between Pre-to post (three months) chemotherapy
Canadian Occupational Performance Measure - COPM assesses perceived daily performance and performance satisfaction with meaningful daily activities. During the pre-chemotherapy assessment, participants will identify up to five activities that they prioritize as meaningful for them. Each of these activities is then rated on a 10-point scale for perceived performance (1=not able to do at all, 10=able to do extremely well) and similarly for satisfaction with performance. The final scores of the COPM are the average scores for total performance and for satisfaction (higher scores indicate better performance or satisfaction with performance). During the post-chemotherapy assessment, the participants will rate the same activities they prioritized in the pre-chemotherapy assessment.
次要结局
- Cognitive Self Efficacy FACT-Cognitive Function questionnaire(Change between Pre-to post (three months) chemotherapy)
- Emotional Well-Being FACT-G questionnaire(Change between Pre-to post (three months) chemotherapy)
- Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-F)(Change between Pre-to post (three months) chemotherapy)
- Reintegration to Normal Living index.(Change between Pre-to post (three months) chemotherapy)
- Backward Digit Span.(Change between Pre-to post (three months) chemotherapy)
- Cognitive performance-based assessment will be assessed by the Weekly Calendar Planning Activity.(Change between Pre-to post (three months) chemotherapy)
- Dual Tasking by performing two tasks concurrently (motor by the Box & Blocks Test and cognitive by backward subtraction for one minute)(Change between Pre-to post (three months) chemotherapy)
- Color Trail Test - CTT(Change between Pre-to post (three months) chemotherapy)
- Qualitative open-ended questions regarding perceived changes in participants' cognitive functioning following cancer diagnosis and how these changes affect their daily functioning(Pre chemotherapy)
- Qualitative open-ended questions regarding perceived changes in participants' cognitive functioning following chemotherapy and how these changes affect their daily functioning(Post (three months) chemotherapy)
研究者
abed.agbarya
Dr.
Bnai Zion Medical Center