Comparison of two different doses of intravenous ketamine (intravenous anesthetic agent) added to intravenous dexmedetomidine (sedative) for awake fibre optic nasotracheal intubatio
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: 8- Other Procedures
- Registration Number
- CTRI/2021/11/038037
- Lead Sponsor
- Goa Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Patients with predicted airway posted for surgery under general anaesthesia
ASA grade I and II
Exclusion Criteria
1.Uncooperative patient/inability to communicate effectively
2.Pregnant women or patients requiring rapid sequence induction
3.Cardiopulmonary disease, heart rate (HR) <50 beats/min or any type of atrioventricular block on the electrocardiogram
4.Allergy to the drugs involved in the study
5.History of drug or alcohol abuse, and patients on long-term opioids or sedative medication
6.Contraindication for nasal intubation
7.Patients of difficult airway with impending airway obstruction
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess time taken for intubation on administration of two different doses of intravenous ketamine added to intravenous dexmedetomidine for awake fibre optic nasotracheal intubationTimepoint: To assess time taken for intubation on administration of two different doses of intravenous ketamine added to intravenous dexmedetomidine for awake fibre optic nasotracheal intubation from the point of introduction of the bronchoscope into the nares of the patient until securing the nasotracheal tube at the level of carina (which will be confirmed by direct visualization of trachea and carina using bronchoscope and capnography to exclude esophageal intubation.
- Secondary Outcome Measures
Name Time Method Assessing variation in following parameters ie heart rate, Systolic blood pressure, Diastolic blood pressure, Mean Arterial pressure, Oxygen Saturation during the procedure of awake fibreoptic bronchoscope guided nasotracheal intubation. <br/ ><br>Timepoint: At following points above parameters will be measured ,besides time taken to reach these points will also be recorded <br/ ><br>1.After insertion of scope <br/ ><br>2.Scope at nasopharynx <br/ ><br>3.Scope at Glottis <br/ ><br>4.After intubation <br/ ><br> 1min <br/ ><br> 5min <br/ ><br>