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Clinical Trials/NCT01838811
NCT01838811
Completed
Not Applicable

Applying Speed of Processing Training (SPT) to Individuals With TBI

Kessler Foundation1 site in 1 country20 target enrollmentNovember 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Traumatic Brain Injury
Sponsor
Kessler Foundation
Enrollment
20
Locations
1
Primary Endpoint
Processing Speed Performance
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

This pilot study will document the efficacy of a behavioral intervention for Processing Speed (PS) in Traumatic Brain Injury (TBI), Speed of Processing Training (SPT), which has been successful used in the aging population in several studies. This study will (1) apply a treatment protocol for PS impairments, well-validated in aging, to persons with TBI with impaired PS, and document its efficacy on standard neuropsychological (NP) tests (2) assess the effectiveness of the intervention utilizing global measures of daily life, including an objective measure (TIADL) (3) examine the long term impact of SPT. This study is unique in that it will be the first to evaluate the efficacy of a highly-manualized structured behavioral treatment for processing speed deficits in persons with TBI utilizing the optimal methodology for carrying out such studies, a randomized clinical trial. Given the prevalence of PS deficits in the TBI population and the significant impact such deficits have on everyday functioning, public safety, and overall quality of life, the identification of an effective intervention for PS deficits in TBI could have a profound impact on the population and society as a whole.

Registry
clinicaltrials.gov
Start Date
November 2011
End Date
December 2013
Last Updated
11 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Kessler Foundation
Responsible Party
Principal Investigator
Principal Investigator

Nancy Chiaravalloti

Director, Neuropsychology & Neuroscience Lab

Kessler Foundation

Eligibility Criteria

Inclusion Criteria

  • fluent in English
  • processing speed impairment (based on evaluation).

Exclusion Criteria

  • currently taking steroids and /or benzodiazepines
  • prior stroke or neurological disease
  • history of significant psychiatric illness (for example, bipolar disorder, schizophrenia, or psychosis) or a current diagnosis of Major Depressive Disorder, Schizophrenia, Bipolar Disorder I or II.
  • significant alcohol or drug abuse history

Outcomes

Primary Outcomes

Processing Speed Performance

Time Frame: week 6 and week 12

Neuropsychological tests which measure processing speed will be used to determine whether there has been a change in performance.

Study Sites (1)

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