Real-time tumor-tracking proton beam therapy for lung cancer
- Conditions
- Primary lung cancer
- Registration Number
- JPRN-UMIN000016575
- Lead Sponsor
- Department of Radiation Medicine, Hokkaido University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 31
Not provided
1)With active infections in the irradiated sites 2)With active other cancers 3)With severe uncontrolled diabetes 4)With severe renal failure which needed dialysis 5)With severe heart disease, or some serious complications, i.e., SLE, Scleroderma, interstitial pneumonia 6)Previous thoracic irradiation 7)Previous chemotherapy within 12 months before enrollment 8)FEV 1.0 under 700 ml 9)With implantable cardioverter defibrillator or permanent pacemaker 10)Pregnancy 11)Considered that participation in this trial is difficult because of psychiatric symptoms or psychosis 12)Cannot be held rest for about 30 minutes 13)Weight over 135 kg 14)Cannot be implanted Au marker in the lung 15)Allergic to radiation 16)Unsuitable for enrollment judged by principal investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of radiation pneumonitis at six months after real-time tumor-tracking proton beam therapy
- Secondary Outcome Measures
Name Time Method 3-year overall survival, local control, progression free survival, recurrence pattern, incidence of adverse effect, incidence of dropout and migration of Au markers during treatment period