Australian Multicentre Colonic Endoscopic Mucosal Resection Study
- Conditions
- Colonic Polyps
- Interventions
- Procedure: Endoscopic Mucosal Resection
- Registration Number
- NCT01368289
- Lead Sponsor
- Professor Michael Bourke
- Brief Summary
A prospective, multicentre, observational study of all patients referred for endoscopic resection of sessile colorectal polyps sized ≥20 mm conducted with intention to treat analysis.
- Detailed Description
A prospective, multicentre, observational study of all patients referred for endoscopic resection of sessile colorectal polyps sized ≥20 mm conducted with intention to treat analysis. Detailed data regarding lesion characteristics (size, location, Paris classification, granular or non-granular surface morphology and Kudo pit pattern), procedural, clinical and histological outcomes and complications are noted. Multivariate analysis will be performed to identify risk factors for Endoscopic Mucosal Resection failure and adenoma recurrence at follow-up colonoscopy.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 3072
- Large sessile polyp (equal to or greater than 20mm)
- Intention to perform EMR
- Aged 18 years or older
- Colonic polyps less than 20mm
- Aged younger then 18 years.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Colonic Polyps Endoscopic Mucosal Resection Patients who present with colonic polyps \>20mm
- Primary Outcome Measures
Name Time Method Technical success for Endoscopic resection 6-60 months To determine the safety, efficacy and predictors of success for Endoscopic Mucosal Resection of large sessile colorectal polyps. The utility of endoscopic criteria to stratify for the risk of Submucosal Invasive Cancer was also assessed.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Westmead Hospital
🇦🇺Westmead, New South Wales, Australia