Surgery of failing dental implants using two different brands of bovine bone chips
- Conditions
- Peri-implantitisOral Health
- Registration Number
- ISRCTN14347002
- Lead Sponsor
- Academic Center for Dentistry Amsterdam
- Brief Summary
2020 results in https://doi.org/10.1111/clr.13651 (added 11/09/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 25
1. During surgical exploration an intra-bony component of at least 3 mm at the deepest point must be present.
2. The defect should have a minimum of 3 osseous walls (a circumference of the osseous defect of at least 270 degrees). Only 3 and 4 wall intraosseous defects will be included
3. The defect must not be wider than 4 mm and the defect angle must be less than 35 degrees from axis of implant
Note: If the same patient has more than one defect meeting the inclusion criteria only one such defect will be included in the study and the other defects will be treated with standard open flap debridement
1. Diabetes mellitus (HbAlc = 6.5%)
2. Taking corticosteroids or other anti-inflammatory prescription drug
3. Taking medications known to induce gingival hyperplasia
4. Allergic to penicillin or metronidazole
5. History of taking systemic antibiotics in the preceding month
6. Pregnant or lactating
7. Stability of the Endobon® granules or control granules cannot be accomplished in the defect
8. Failure of obtaining soft tissue closure
9. Mobile implants
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vertical radiographic bone fill of peri-implant intra-bony defects measured on the basis of standardized intraoral periapical radiographs at at baseline, 6 months and 12 months
- Secondary Outcome Measures
Name Time Method <br> All measured at 6 sites/implant at baseline, 6 months and 12 months:<br> 1. Pocket probing depth<br> 2. Bleeding on probing<br> 3. Dichotomous scoring of suppuration (pus)<br> 4. Dichotomous scoring of plaque<br>