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临床试验/CTRI/2024/01/061732
CTRI/2024/01/061732尚未招募Phase 3 4

A Comparision of efficacy of Dexamethasone and methylprednisolone used as an adjuvant with 0.5%Ropivacaine under ultrasound guided supraclavicular brachial plexus block

JLN medical college1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2024年1月24日最近更新:

试验速览

阶段
Phase 3 4
状态
尚未招募
发起方
入组人数
80
试验地点
1
主要终点
Duration of Analgesia

研究概览

简要总结

this will be a double blinded randomized study conducted to evaluate and compare inj. dexamethasone 8mg  and inj. methylprednisolone 40 mg as an adjuvent with inj. Ropivacaine 0.5% 30 ml given  as USG guided supraclavicular block in patients undergoing various orthopaedic surgical procedure around elbow and forearm  with a primary objective to compare duration of analgesia and secondary objectives being onset and duration of sensory block, onset and duration of motor block, and adverse effect . Participants will be allocated in to group RD who will be receiving inj. dexamethasone and group RM who receiving inj. methylprednisolone  with local anaesthetic agent in doses as described earlier and will be monitored intraoperatively and post operatively at described interval and study parameters will be recorded  and data will be analysed using standard  qualitative and quantitative test . P value of less than 0.05 will be considered significant.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.body weight 40kg to 80kg 2.patient belong to ASA I and II 3.Patient undergoing various orthopaedic surgeries around elbove and forearm.

排除标准

  • 1.patient refusal
  • ASA grade III and more
  • pregnancy
  • neuropathy of surgical limb
  • local pathology at site of injection od drug.

结局指标

主要结局

Duration of Analgesia

时间窗: Pain is assessed using VAS SCORE at immediate post operatively then at every 1 hr interval till 24 hr

次要结局

  • 1.Onset & Duration of Sensory block(2.Onest & Duration of Motor block)

研究者

发起方
JLN medical college
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

DrARVIND KHARE

Jawahar lal nehru medical college

研究点 (1)

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