A Comparision of efficacy of Dexamethasone and methylprednisolone used as an adjuvant with 0.5%Ropivacaine under ultrasound guided supraclavicular brachial plexus block
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Duration of Analgesia
研究概览
简要总结
this will be a double blinded randomized study conducted to evaluate and compare inj. dexamethasone 8mg and inj. methylprednisolone 40 mg as an adjuvent with inj. Ropivacaine 0.5% 30 ml given as USG guided supraclavicular block in patients undergoing various orthopaedic surgical procedure around elbow and forearm with a primary objective to compare duration of analgesia and secondary objectives being onset and duration of sensory block, onset and duration of motor block, and adverse effect . Participants will be allocated in to group RD who will be receiving inj. dexamethasone and group RM who receiving inj. methylprednisolone with local anaesthetic agent in doses as described earlier and will be monitored intraoperatively and post operatively at described interval and study parameters will be recorded and data will be analysed using standard qualitative and quantitative test . P value of less than 0.05 will be considered significant.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •1.body weight 40kg to 80kg 2.patient belong to ASA I and II 3.Patient undergoing various orthopaedic surgeries around elbove and forearm.
排除标准
- •1.patient refusal
- •ASA grade III and more
- •pregnancy
- •neuropathy of surgical limb
- •local pathology at site of injection od drug.
结局指标
主要结局
Duration of Analgesia
时间窗: Pain is assessed using VAS SCORE at immediate post operatively then at every 1 hr interval till 24 hr
次要结局
- 1.Onset & Duration of Sensory block(2.Onest & Duration of Motor block)
研究者
DrARVIND KHARE
Jawahar lal nehru medical college
