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Clinical Trials/DRKS00031382
DRKS00031382
Recruiting
未知

Transcutaneous Vagal Nerve Stimulation for the Treatment ofPersistent Atrial Fibrillation (VAST-AF): a Randomized, Controlled,Blinded, Monocentric, Clinical Trial - VAST-AF

Marienhaus Klinikum Hetzelstift0 sites120 target enrollmentMarch 3, 2023

Overview

Phase
未知
Intervention
Not specified
Conditions
I48.1
Sponsor
Marienhaus Klinikum Hetzelstift
Enrollment
120
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
March 3, 2023
End Date
TBD
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
Marienhaus Klinikum Hetzelstift

Eligibility Criteria

Inclusion Criteria

  • Persistend atrial fibrillation
  • Planned electric cardioversion
  • Sufficient oral anticoagulation for at least four weeks or
  • Absence of thrombus in TEE
  • Oral anticoagulation possible
  • Able to sign informed consent
  • Estimated life expectancy \>1 year

Exclusion Criteria

  • Permanent atrial fibrillation
  • Ablation therapy of supraventricular arrhythmias in the past
  • Missing anticoagulation respective missing rule out of thrombus
  • Inability to treat with oral anticoagulation
  • Latent or manifest hyperthyroidism
  • Acute infection with relevant clinical signs (temp \> 38°C, significant elevated CRP or WBC)
  • Inability to sign informed consent
  • Preexisting pacemaker or ICD
  • Recent vagal stimulation for other causes
  • Recent intolerance of transcutaneous vagal stimulation

Outcomes

Primary Outcomes

Not specified

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