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临床试验/PACTR202001797822250
PACTR202001797822250尚未招募1 期

The early use of steroid therapy in reducing chemotherapy induced myocarditis following cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy in the early post-operative period: A retrospective study

ational cancer institute0 个研究点目标入组 60 人开始时间: 2019年12月31日最近更新:
适应症

试验速览

阶段
1 期
状态
尚未招募
发起方
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
19 Year(s) 至 44 Year(s)(—)
性别
All

入选标准

  • Greater than or equal to 18 years of age.
  • Clinical performance status of ECOG = 2.
  • Stable serum CEA levels not indicating recurrence.
  • No history of prior/other malignancies within the 2 years prior to enrollment with the exception of basal cell carcinoma.

排除标准

  • Active systemic infections, coagulation disorders, or other major medical illnesses precluding major surgery.
  • Prior experimental therapy with novel agents.
  • Prior HIPEC.
  • History of brain metastases.
  • Childs B or C cirrhosis or with evidence of severe portal hypertension by history, endoscopy, or radiologic studies or with evidence of moderate to severe ascites.
  • Weight less than 40 kg.
  • History of congestive heart failure and/or an LVEF < 40%.
  • Significant COPD or other chronic pulmonary restrictive disease with PFT's indicating an FEV1 less than 50% or a DLCO less than 40% predicted for age.

研究者

发起方
ational cancer institute

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