effect of Gemfibrozil for treatment of cigarette
- Conditions
- nicotine dependence.Mental and behavioural disorders due to use of tobacco
- Registration Number
- IRCT2017101732057N3
- Lead Sponsor
- Vice chancellor for research of Kashan University of Medical Sciences and Health Services
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 76
Having an age of 19–65 years; nicotine dependence based on DSM 5; lack of history of psychotic disorders; having negative results in opioid and amphetamines test; lacking diagnosis of chronic disease such as debate, blood pressure , cancer and etc; Not be pregnant. Exclusion criteria: Unwillingness to continue participating in the study; being pregnancy during study; uses drugs with contraindication or Interference with Gemfibrozil such as Anticoagulants, statins, other fibrates and niacin.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Smoking cessation. Timepoint: Before intervention; 1,2,3,4,5,6,7,8,11,14,19 after beginning of intervention. Method of measurement: Expiratory CO2 concentration.;Nicotine dependence. Timepoint: Before intervention; 1,2,3,4,5,6,7,8,11,14,19 after beginning of intervention. Method of measurement: fagestrom nicotine dependence scale.;Nicotine Withdrawal. Timepoint: Before intervention; 1,2,3,4,5,6,7,8,11,14,19 after beginning of intervention. Method of measurement: Minnesota Nicotine Withdrawal Scale.
- Secondary Outcome Measures
Name Time Method