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Community-based Rehabilitation and Fall Prevention Program After Total Knee Arthroplasty

Not Applicable
Conditions
Knee Osteoarthritis
Fall
Interventions
Other: Fall prevention program
Registration Number
NCT03615638
Lead Sponsor
The Hong Kong Polytechnic University
Brief Summary

Knee osteoarthritis (OA) is a common musculoskeletal disorder among older people. Since the prevalence of knee OA increases with age, it is anticipated that the prevalence and burden of knee OA will increase significantly given the aging population.

Total knee arthroplasty (TKA) is used to treat patients with severe knee OA. While TKA has been shown to improve knee pain, function and quality of life of patients with knee OA, up to 50% of patients with post-TKA may suffer from falls within in the first year after TKA. Given that Tai Chi can significantly improve the balance and function of older people, a fall prevention program may improve balance, pain, and function of post-TKA patients.

As such, the current 3-arm randomized controlled trial (RCT) aims to compare the effectiveness of a post-operative community-based fall prevention program in improving knee pain, function and balance of patients with unilateral TKA against a group of TKA patients receiving standard post-operative care, and age- and gender-matched asymptomatic controls over 1 year.

Detailed Description

Osteoarthritis (OA) is the third most disabling musculoskeletal compliant in the world. Knee OA is the most common type of OA. Since the prevalence of knee OA increases with age, it is anticipated that the prevalence and burden of knee OA will increase significantly given the aging population.

Total knee arthroplasty (TKA) is a surgical intervention for treating patients with severe knee OA. Research has found that TKA reduces knee pain, and improves patient's function and quality of life. However, studies have also found that patients with post-TKA may be more likely to fall as compared to age- and gender-matched asymptomatic counterparts. It is estimated that around 20% to 50% of patients fall within in the first year after TKA. As such, it is essential to improve the balance of post-TKA patients.

Studies have found that Tai Chi can significantly improve the balance and function of older people. Therefore, a fall prevention program aiming at strengthening, proprioception, balance training, and behavioral modification may improve balance, pain, and function of post-TKA patients.

As such, the current 3-arm randomized controlled trial (RCT) aims to compare the effectiveness of a post-operative community-based fall prevention program in improving knee pain, function and balance of patients with unilateral TKA with a group of patients receiving standard post-operative care, and age- and gender-matched asymptomatic controls over 1 year.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
78
Inclusion Criteria
  • Participants undergoing TKA for intervention group and usual postoperative care group
  • Age- and gender-matched asymptomatic controls without knee pain in the last 12 months.
  • Can speak and understand Cantonese/English.
Exclusion Criteria
  • Living in assisted living facilities, requiring nursing care
  • Medical 'red flag' conditions
  • A history of cancer in the last five years
  • Cauda equine syndrome
  • Knee fracture
  • Auto-immune disease (e.g. rheumatoid arthritis) even if they have OA
  • Inflammatory or septic arthritis
  • Systemic disease
  • Amputation
  • History of orthopedic or neurological surgery to the spine, pelvis or hips
  • Neurological diseases (e.g. stroke or Parkinson's disease)
  • Mini-Mental State Examination score < 24
  • Depression subscale score of Depression Anxiety Stress Scales > 21
  • Severe comorbidity leading to severe deterioration of quality of life or major healthcare utilization
  • Osteochondritis dissecans
  • Perthes' disease
  • Plica disease
  • Baker's cyst

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Fall prevention groupFall prevention programFall prevention program
Primary Outcome Measures
NameTimeMethod
Chinese version of Knee Injury and Osteoarthritis Outcome Scale1 year

A 42-item questionnaire with 5 subscales to assess pain, symptoms, activities of daily living, sports and recreation function, and knee-related quality of life

Secondary Outcome Measures
NameTimeMethod
Chinese version Falls Efficacy Scale - International1 year

To examine a person's confidence in avoiding a fall during 16 non-threatening activities of daily living.

Chinese version geriatric depression scale1 year

It consists of 15 questions to assess depression in older people

Number of post-operative trips/falls1 year

To quantify the number of trips/falls over 1 year after TKA

Physical Activity Scale for the Elderly1 year

It evaluates leisure, physical, household and work-related activities over the last 7 days

11-point numeric pain rating scale1 year

This scale quantify pain on a scale of 0 to 10. Higher the scores, higher the pain intensity

Chinese version Insomnia Severity Index1 year

It assesses sleep problems and related difficulties

Trial Locations

Locations (2)

Yan Chai Hospital

🇭🇰

Hong Kong, Hong Kong

Queen Mary Hospital

🇭🇰

Hong Kong, Hong Kong

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