a clinical trial to compare efficacy of the analgesic activity of inj. Bupivacaine vs inj. Ropivacaine given at transverse abdominis block and also compare the safety parameters also.
Phase 4
- Registration Number
- CTRI/2017/08/009249
- Lead Sponsor
- Department of Anaesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ï??Informed written consent for
participation in study.
ï??Age: 20-35 years
ï??Gender: Antenatal female patients
scheduled for elective or non urgent
lower segment cesarean section.
ï??ASA physical status I and II.
ï??Patients refusing consent.
Exclusion Criteria
1.Contraindications to Spinal Anaesthesia like,
Local infection or sepsis at the site of
Lumbar puncture
Bleeding disorders, thrombocytopenia
Space occupying lesions of the brain
Anatomical disorders of the spine
Hypovolaemia e.g. following massive
haemorrhage
2.Allergy to local anaesthetic drugs and NSAIDS.
3.Patient on any form of analgesics therapy.
4.BMI >= 25 kg/m2
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare efficacy and safety of bupivacaine and ropivacaine for post operative pain relief in lower segment cesarean section with Visual Analogue Score and total dose of rescue analgesia.Timepoint: 1st day of lower cesarean section(First 24 hours after lower segment cesarean section)
- Secondary Outcome Measures
Name Time Method Effect on hemodynamic variables like Heart Rate (HR), Mean Arterial Pressure (MAP), Oxygen saturation (SpO2). <br/ ><br>Side effects & Complications if any. <br/ ><br>Timepoint: 1st day of lower segment cesarean section (24 hours of lower segment cesarean section)