Effect of Low Power Laser in Tooth Pain Modulation Caused by Irreversible Inflammation

Not Applicable

Completed

• Conditions: Acute Pain; Pulpitis
• Interventions: Radiation: Sham Laser Irradiation; Radiation: Laser 1 (at 0,16 Joules/point of irradiation); Radiation: Laser 2 (1,6 Joules/point of irradiation); Other: No additional Intervention (control)

• Registration Number: NCT02169102
• Lead Sponsor: University of Sao Paulo

Brief Summary

Anxiety, pain and discomfort are common stressful situations that occur during the dentistry practice, especially in the urgency endodontic practice. Studies have concluded that low intensity laser therapy is effective in treating pain. However, most studies have reported the low intensity laser therapy in chronic pain, few studies have shown its application on acute pain and none have evaluated the low intensity laser´s analgesic effect in acute pain of the pulp inflammation. Since the pulp tissue has the peculiar characteristic to be surrounded by dentin, in acute pulpits, the inflammatory reaction is more complicated than usual. Furthermore, during the inflammatory process, sometimes anesthesia is not always completely effective. Thus, this present study aims to evaluate whether previous therapy with low intensity laser could, by its analgesic effect, promote greater comfort especially to this type of patient. 60 patients with acute pulpits pain will be selected to this study (randomized and double-blinded) and they will be divided in 4 groups:

Group 1 ( n=15) - Control Group; Group 2 (n=15) - Laser 1: 780 nanometers (nm); 40 milliwatts (mW); 4 seconds per point; 0.16 Joules/point; total irradiated points: 02; Group 3 (n=15) - Laser 2: 780nm; 40 mW; 40 seconds per point; 1.6 Joules/point, total irradiated points: 02; Group 4 (n=15) - Placebo group - Sham Laser Irradiation.

The pain will be evaluated by a visual analogue scale (VAS) in 3 different times: initial pain, pain immediately after and 15 minutes after interventions (laser irradiation, or sham laser irradiation). After that, patients with acute pulp irreversible inflammation will be submitted to conventional endodontic urgency treatment. Data concerning the need of complimentary local anesthesia will be also taken into account. Data of different groups and times will be statistically compared.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-02
• Primary Completion: 2014-06
• Study First Submitted: 2014-06-18
• Study First Submitted QC: 2014-06-19
• Study First Posted: 2014-06-20
• Study Completion: 2014-10
• Status Verified: 2015-04
• Last Update Submitted: 2015-04-10
• Last Update Posted: 2015-04-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients with acute pain due to irreversible inflammation of the a vital pulp tooth

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Exclusion Criteria

• Non-Intact Pulp chamber
• Necrotic pulp

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Sham Laser	Sham Laser Irradiation	-
Laser 1	Laser 1 (at 0,16 Joules/point of irradiation)	Low Power Laser applied at 0.16 Joules/point. 2 points of laser irradiation
Laser 2	Laser 2 (1,6 Joules/point of irradiation)	Low Power Laser applied at 16 Joules/point. 2 points of laser irradiation
Control	No additional Intervention (control)	-

Primary Outcome Measures

Name	Time	Method
Tooth pain modulation during irreversible pulp inflammation after low power laser irradiation	Immediately after low power laser irradiation and 15 minutes after low power laser irradiation	Pain will be measured through VAS (Visual Analog Scale).

Secondary Outcome Measures

Name	Time	Method
Need of anesthetic supplementation during urgency endodontic treatment	15 minutes	15 minutes after low power laser irradiation, patients will be submitted to endodontic urgency treatment adopted in School of Dentistry of University of São Paulo. The need of local anesthetic supplementation will be observed between the patients

Trial Locations

Locations (1)

School of Dentistry - University of São Paulo; 🇧🇷 São Paulo, Brazil