Effect of Low Power Laser in Pain Modulation During Irreversible Inflammation of Tooth Pulp
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Tooth pain modulation during irreversible pulp inflammation after low power laser irradiation
研究概览
简要总结
Anxiety, pain and discomfort are common stressful situations that occur during the dentistry practice, especially in the urgency endodontic practice. Studies have concluded that low intensity laser therapy is effective in treating pain. However, most studies have reported the low intensity laser therapy in chronic pain, few studies have shown its application on acute pain and none have evaluated the low intensity laser´s analgesic effect in acute pain of the pulp inflammation. Since the pulp tissue has the peculiar characteristic to be surrounded by dentin, in acute pulpits, the inflammatory reaction is more complicated than usual. Furthermore, during the inflammatory process, sometimes anesthesia is not always completely effective. Thus, this present study aims to evaluate whether previous therapy with low intensity laser could, by its analgesic effect, promote greater comfort especially to this type of patient. 60 patients with acute pulpits pain will be selected to this study (randomized and double-blinded) and they will be divided in 4 groups:
Group 1 ( n=15) - Control Group; Group 2 (n=15) - Laser 1: 780 nanometers (nm); 40 milliwatts (mW); 4 seconds per point; 0.16 Joules/point; total irradiated points: 02; Group 3 (n=15) - Laser 2: 780nm; 40 mW; 40 seconds per point; 1.6 Joules/point, total irradiated points: 02; Group 4 (n=15) - Placebo group - Sham Laser Irradiation.
The pain will be evaluated by a visual analogue scale (VAS) in 3 different times: initial pain, pain immediately after and 15 minutes after interventions (laser irradiation, or sham laser irradiation). After that, patients with acute pulp irreversible inflammation will be submitted to conventional endodontic urgency treatment. Data concerning the need of complimentary local anesthesia will be also taken into account. Data of different groups and times will be statistically compared.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with acute pain due to irreversible inflammation of the a vital pulp tooth
排除标准
- •Non-Intact Pulp chamber
- •Necrotic pulp
研究组 & 干预措施
Control
干预措施: No additional Intervention (control) (Other)
Sham Laser
干预措施: Sham Laser Irradiation (Radiation)
Laser 1
Low Power Laser applied at 0.16 Joules/point. 2 points of laser irradiation
干预措施: Laser 1 (at 0,16 Joules/point of irradiation) (Radiation)
Laser 2
Low Power Laser applied at 16 Joules/point. 2 points of laser irradiation
干预措施: Laser 2 (1,6 Joules/point of irradiation) (Radiation)
结局指标
主要结局
Tooth pain modulation during irreversible pulp inflammation after low power laser irradiation
时间窗: Immediately after low power laser irradiation and 15 minutes after low power laser irradiation
Pain will be measured through VAS (Visual Analog Scale).
次要结局
- Need of anesthetic supplementation during urgency endodontic treatment(15 minutes)
研究者
Karen Müller Ramalho
PhD
University of Sao Paulo
