MedPath

A cognitive, occupation-based programme for people with multiple sclerosis (COB-MS)

Not Applicable
Completed
Conditions
Multiple sclerosis
Nervous System Diseases
Registration Number
ISRCTN11462710
Lead Sponsor
I Galway
Brief Summary

2020 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/32183874 protocol (added 19/03/2020) 2023 Other publications in https://pubmed.ncbi.nlm.nih.gov/37493191/ (added 27/07/2023) 2024 Preprint results in https://doi.org/10.21203/rs.3.rs-4151380/v1 (added 28/03/2024)

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
94
Inclusion Criteria

People with MS:
1. Aged 18 years of age or older
2. Fluent in written and spoken English
3. Diagnosis of multiple sclerosis
4. Cognitive difficulties, as shown by a score of >22 on the MSNQ
5. Clinically stable (we define clinically stable” as not having an active relapse)
6. Can provide informed consent
7. No neurologic history other than MS, including evidence of current dementia
8. No history of major depressive disorder, schizophrenia, or bipolar disorder I or II
9. No history of diagnosed substance use or dependence disorder
10. Not currently undergoing any other form of cognitive rehabilitation
11. Living in the community

Occupational Therapists:
1. Currently working in Ireland as an occupational therapist
2. CORU-registered
3. Have experience working with people with MS
4. Can commit to the requirements of the study

Exclusion Criteria

People with MS:
1. Cognitive impairment that would affect reliable participation or capacity to give informed consent
2. Are incarcerated or institutionalized
3. Significant neurological condition or organic brain damage (unrelated to MS).

Occupational Therapists:
1. Not meeting the inclusion criteria

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Goal Attainment Scaling at the 12-week follow-up
Secondary Outcome Measures
NameTimeMethod
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