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Clinical Trials/ISRCTN11462710
ISRCTN11462710
Completed
未知

A Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS): a randomised pilot trial to improve cognition and daily functioning for people with multiple sclerosis

I Galway0 sites94 target enrollmentSeptember 4, 2019

Overview

Phase
未知
Intervention
Not specified
Conditions
Multiple sclerosis
Sponsor
I Galway
Enrollment
94
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

2020 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/32183874 protocol (added 19/03/2020) 2023 Other publications in https://pubmed.ncbi.nlm.nih.gov/37493191/ (added 27/07/2023) 2024 Preprint results in https://doi.org/10.21203/rs.3.rs-4151380/v1 (added 28/03/2024)

Registry
who.int
Start Date
September 4, 2019
End Date
July 1, 2022
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
I Galway

Eligibility Criteria

Inclusion Criteria

  • People with MS:
  • 1\. Aged 18 years of age or older
  • 2\. Fluent in written and spoken English
  • 3\. Diagnosis of multiple sclerosis
  • 4\. Cognitive difficulties, as shown by a score of \>22 on the MSNQ
  • 5\. Clinically stable (we define clinically stable” as not having an active relapse)
  • 6\. Can provide informed consent
  • 7\. No neurologic history other than MS, including evidence of current dementia
  • 8\. No history of major depressive disorder, schizophrenia, or bipolar disorder I or II
  • 9\. No history of diagnosed substance use or dependence disorder

Exclusion Criteria

  • People with MS:
  • 1\. Cognitive impairment that would affect reliable participation or capacity to give informed consent
  • 2\. Are incarcerated or institutionalized
  • 3\. Significant neurological condition or organic brain damage (unrelated to MS).
  • Occupational Therapists:
  • 1\. Not meeting the inclusion criteria

Outcomes

Primary Outcomes

Not specified

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