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Clinical Trials/NCT01943149
NCT01943149
Unknown
N/A

E-MAX 2nd Generation Vitamin E Polyethylene On BIOLOX Delta Ceramic Heads

Renovis Surgical Technologies, Inc.1 site in 1 country50 target enrollmentJanuary 2014

Overview

Phase
N/A
Intervention
Not specified
Conditions
In Need of a Total Hip Arthroplasty
Sponsor
Renovis Surgical Technologies, Inc.
Enrollment
50
Locations
1
Primary Endpoint
E-Max liner wear rate
Last Updated
10 years ago

Overview

Brief Summary

The purpose of this study is to monitor outcomes of total hip arthroplasties performed with E-MAX polyethylene and BIOLOX Delta Ceramic head. Polyethylene has been used as a bearing surface in total joint replacements for half of a century. Radiation, the most common form of sterilization, unfortunately it results in the creation of free radicals (atoms or molecules that cause chemical reactions with other substances) within the materials which cause the breakdown of the polyethylene. Second generation antioxidant polyethylene, Renovis E-MAX, mechanically blends in Vitamin E as an antioxidant. This helps eliminate free radicals while maintaining mechanical strength. The theory is that E-MAX will be a safe and long lasting bearing surface in total hip arthroplasty that meets or exceeds current wear rates after being placed in a patient.

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
January 2024
Last Updated
10 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Renovis Surgical Technologies, Inc.
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient is under 65 years of age
  • Patient's health status qualifies as ASA 1 or ASA 2
  • Patient is willing to commit to long term follow (study duration is 10 yrs)

Exclusion Criteria

  • Allergy to any materials used in hip implant
  • Unwillingness to participate in long term follow-up
  • Diagnosis of inflammatory arthritis
  • Simultaneous bilateral total hip arthroplasty is recommended.
  • Patient's health status qualifies as ASA 3 or greater.
  • Patient is over the age of 65 of age

Outcomes

Primary Outcomes

E-Max liner wear rate

Time Frame: Change from baseline to 10 years post-operative

This measure's purpose it to look at the longevity of our product. Radiographs will be taken at standard checkpoints over the course of 10 years. Radiographic analysis will be done to assess wear rates of the E-Max liner over the course of the 10 year study. Wear rates will then be compared to other products that have already been studied and published in hopes of finding that E-Max's wear rates are at least as good if not better than comparative products on the market.

Secondary Outcomes

  • Patient Function and Mobility(Change from Pre-operative to 10 years post-operative)

Study Sites (1)

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