KCT0003432
Completed
未知
Comparative Study on Effect of Pharmacological Stress with Nicorandil and Adenosine to Diagnostic Performance of Myocardial Perfusion SPECT in Ischemic Heart Diseases
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Kangwon National University Hospital
- Enrollment
- 50
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •? suspected ischemic heart disease patient who will undergo coronary angiography
- •a) previously healthy patient: no previous medical history with diagnosis of or treatment for coronary heart disease
- •b) known ischemic heart disease patient: patient with new symptoms including chest pain, dyspnea, etc. within recent 1 month
- •? both male and female patients aged over 40
Exclusion Criteria
- •? Severe renal failure, hepatic failure, brain function disorders, hypotension, cardiogenic shoke, or other physical or psycological problems that make the patient difficult to participate in the current study
- •? contraindications to adenosine or nicorandil as below:
- •a) adenosine: hypersensitivity reaction, 2nd/3rd degree AV block, sick sinus syndrome, chronic obstructive pulmonary disease, long QT syndrome, severe hypotension, uncompensated heart failure, refractory unstable angina, dipyridamol use
- •b) nicorandil: severe hepatic/renal dysfunction, severe brain dysfunction, severe hypotension or cardiogenic shock, Eisenmenger syndrome or primary hypertension, right ventricular infarction, dehydration symptoms, neurocirculatory asthenia,
- •narrow angle glaucoma, history of hypersensitiveness to nicorandil or nitric acid/nitrite ester agents, use of phosphodiesterase\-5 (PDE\-5\) or guanylate cyclase
- •? pregnancy or breast feeding
Outcomes
Primary Outcomes
Not specified
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