Comparative study of 1064nm Q-switched ND:YAG laser and Er:YAG2940nm laser in treatment of macular amyloidosis

Not Applicable

Recruiting

• Conditions: macular amyloidosis.; Organ-limited amyloidosis; E85.4

• Registration Number: IRCT20200811048363N1
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 April 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

Patients with macular amyloidosis clinical symptoms
Patients with at least 5 to 10 cm2 macular amyloidosis skin lesion on the trunk or limbs
At least 6 months have passed since the onset of skin lesion

Exclusion Criteria

Pregnancy, breastfeeding or deciding to get pregnant in the next 2 months
Personal history of hypertrophic scar or keloid formation
Personal history of melanoma or other skin cancers
History of systemic retinoid therapy during last 6 months
History of any systemic treatment during the last 3 months for macular amyloidosis
history of any topical treatment during the last month for macular amyloidosis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intensity changes of pigmentation. Timepoint: Before the intervention (0) ; 4 weeks after the last session of intervention. Method of measurement: photography with a single camera.;Intensity changes of pigmentation. Timepoint: Before the intervention (0) ; 4 weeks after the last session of intervention. Method of measurement: Questionnaire with Visual Analogue Scale.;Intensity changes of itching. Timepoint: Before the intervention (0) ; 4 weeks after the last session of intervention. Method of measurement: Questionnaire with Visual Analogue Scale.