MRI Functional Imaging Characteristics and Fat Quantification of CT-fat-free Renal Neoplasms: Relationships With Histological Classifications and Molecular Markers
Not Applicable
Active, not recruiting
- Conditions
- Kidney Neoplasms
- Registration Number
- NCT06126159
- Lead Sponsor
- Chang Gung Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
Inclusion Criteria:<br><br> 1. Age = 20 years old<br><br> 2. Have renal parenchymal masses with no detectable intra-tumoral fat on computed<br> tomography (CT)<br><br> 3. Normal renal function (i.e.: estimated glomerular filtration rate ? 60 mL/min/1.73<br> m2)<br><br> 4. No allergy history of iodinated contrast medium<br><br>Exclusion Criteria:<br><br> 1. Pregnant or lactating woman<br><br> 2. Withdrawal of informed consent<br><br> 3. Those who have not completed MRI<br><br> 4. Those who did not receive renal tumor biopsy
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MR characteristics assessment- T2WI;MR characteristics assessment- ADC;MR characteristics assessment- IVIM
- Secondary Outcome Measures
Name Time Method Quantitative Real-Time polymerase chain reaction (qPCR);Immunohistochemistry (IHC) statin- mTOR;Immunohistochemistry (IHC) statin- Phospho-mTOR;Immunohistochemistry (IHC) statin- Rheb;Immunohistochemistry (IHC) statin- S6K;Immunohistochemistry (IHC) statin- pS6K