MedPath

Validation of a Urine-based Assay With Genomic Markers for Predicting Recurrence for Non-muscle Invasive Bladder Cancer

Completed
Conditions
Non-muscle Invasive Bladder Cancer
Registration Number
NCT02969109
Lead Sponsor
Genomic Health®, Inc.
Brief Summary

A study to validate, in a prospective manner, the ability of the predefined Genomic Health bladder cancer assay to detect recurrence in patients undergoing surveillance for non-muscle invasive bladder cancer.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
417
Inclusion Criteria
  • Patients with a prior diagnosis of non-muscle invasive, ≤T1, urothelial cell carcinoma of the bladder scheduled to undergo surveillance cystoscopy.
Exclusion Criteria
  • Patients younger than 18 years
  • Patients with a diagnosis of small cell carcinoma, adenocarcinoma or squamous cell carcinoma of the bladder
  • Patients who have had a cystectomy or prior diagnosis of muscle invasive disease (T2 or greater)
  • Patients who are unable or unwilling to give informed consent

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The recurrence status based on the pathology results1 year
The Genomic Health bladder cancer assay results.1 year
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Institute for Prostate and Urologic Cancers - University of Minnesota

🇺🇸

Minneapolis, Minnesota, United States

© Copyright 2025. All Rights Reserved by MedPath