Drug Interaction With Genes in Parkinson's Disease
试验速览
- 阶段
- 不适用
- 入组人数
- 600
- 试验地点
- 1
- 主要终点
- All complications of the disease or treatment
研究概览
简要总结
This observational study aims at identifying gene modifiers of Parkinson Disease (PD) and of treatment response and adverse events of antiparkinsonian drugs. Six hundred PD patients will be followed annually for up to 5 years. A biological collection will be associated with a full clinical assessment of motor and non motor symptoms, medical and treatment history, environmental factors. The association between candidate gene polymorphisms and disease or treatment complications will be analyzed.
详细描述
Title : Drug interaction with genes in Parkinson Disease
Objective:
To identify genes associated to disease and treatment complication and response.
Number of subjects: 500
Study duration : 6 years
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women, age >
- •Parkinson Disease according to UKPDSBB criteria
- •PD diagnosis < 6 years
- •Informed consent
排除标准
- •Atypical parkinsonism
结局指标
主要结局
All complications of the disease or treatment
时间窗: 5 years
次要结局
未报告次要终点